QSight Triple Quad LC-MS/MS 400 Series | PerkinElmer
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QSight LC/MS/MS System

More than ever, laboratories analyzing food and environmental samples are faced with evolving challenges with stricter regulations demanding lower detection limits and higher levels of productivity. Lab operations need to be optimized, without any compromise on analysis confidence and accuracy.

With the PerkinElmer QSight® Triple Quad LC/MS/MS labs can test for the most challenging samples with maximized uptime and confidence. The unique dual-source configuration enables high-throughput labs to collect data in two complementary modes, maximizing the output from a single injection. Combined with the StayClean technology dramatically reduced source cleaning and maintenance, translating into higher productivity and high ROI. Running on the PerkinElmer Simplicity 3Q Software, the PerkinElmer QSight Triple Quad LC/MS/MS is easy-to-learn and use and it is a complete solution streamlining the complete workflow, from validated method development to data reporting.

Part Number
Model Name
BC003844
QSight 420 LC/MS/MS
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BC003382
QSight 220 LC/MS/MS
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BC003383
QSight 210 LC/MS/MS
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BC003265
QSight 110 LC/MS/MS
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Overview

The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively

  • Sensitivity for the most demanding regulations
  • Easy-to-use with ready to implement methods
  • Patented flow-based technology that enables up to 15% more productivity
  • StayClean Source, self-cleaning design for maximum sensitivity and exceptional uptime
  • Laminar Flow Ion Guide for highly efficient field-free transmission, providing virtually no maintenance requirements
  • Dual Source technology gives you the capability to set ESI or APCI modes, with two independent probes for true multiplexing
  • Modular Simplicity 3Q Software to acquire, quantify, and report with flexible data viewing options and powerful remote diagnostics.
  • Different models available (QSight 110 LC/MS/MS, QSight 210 LC/MS/MS, QSight 220 LC/MS/MS, QSight 420 LC/MS/MS) addressing different levels of performance and efficiency required by different labs’ analysis needs.

Specifications

Model Name QSight 420 LC/MS/MS
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Application Note

A Fully Validated Method for Determination of Twelve Mycotoxins in Various Food Matrices

Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...

PDF 3 MB
A Multiclass Multiresidue Method for Analysis of Veterinary Drugs in Chicken by UHPLC/MS/MS

Veterinary drugs are used in animal production to treat diseases, prevent infection and protect growth of animals, which helps provide quality marketplace. However the uncontrolled use may cause heavy human disease so regulatory agencies around the world have established maximum residue levels (MRLs ...

PDF 1 MB
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS

A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS

PDF 1 MB
A Simple and Sensitive Method for Rapid Determination of PFOA and PFOS in Water Samples by Direct Injection UHPLC/MS/MS

Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced and widely used in industrial applications and consumer products since the 1950s. The unique physical and chemical characteristics of these ...

PDF 1 MB
Analysis of Aflatoxins by UHPLC

Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.

PDF 1 MB
Analysis of Low PPT Levels of Estrogens in Serum without Derivatization Using QSight 420 UHPLC/MS/MS System

Estrogens are steroid hormones derived from cholesterol. They are crucial for the development of female secondary sex characteristics and reproductive functions, and are also important for many other non–sex-specific processes, including growth, skeleton maintenance, cardioprotective, and neuroprote ...

PDF 1 MB
Analysis of Multi-Residue Pesticides in Rice by LC/MS/MS

Due to the large number of pesticides potentially used in rice production, the use of multi-residue methods capable of determining many pesticides in one single run is the most efficient approach. In this study, a fast, sensitive and selective multiresidue method has been developed for analysis of o ...

PDF 1 MB
Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues rel ...

PDF 1 MB
Analysis of Pork Adulterated Meat

A selective and sensitive LC/MS/MS method for fast identification and analysis of meat samples using three peptides specific for pork as biomarkers. . The optimized sample preparation procedure is easy to follow and can be used for analyzing raw, cooked and processed meat products. This method can s ...

PDF 1 MB
Analysis of Target Pesticide Residues in Berries with LC/MS/MS Coupled with a QuEChERS Sample Prep

Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS

PDF 1 MB
Analysis of Tetracycline in Animal Tissue Using UHPLC/MS/MS System equipped with QS-works Autosampler

In order to protect human health, regulatory agencies around the world have established maximum residue levels (MRLs) or tolerances of veterinary drugs in foods. The use of highly sensitive and selective techniques for accurate monitoring of tetracyclines based on regulatory requirements is essentia ...

PDF 1 MB
Analysis of illegal dyes in Chili Spices via UHPLC-MS/MS

Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...

PDF 4 MB
Application Compendium - Analytical Solutions for Pesticides Analysis

The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analysis ...

PDF 6 MB
Determination of Aflatoxin M1 in Milk and Infant Formula by QSight LC-MS-MS

Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...

PDF 949 KB
Determination of Polycyclic Aromatic Hydrocarbons in Seafood by UHPLC- MS/MS

Polycyclic aromatic hydrocarbons (PAHs) can contaminate foods during smoking, heating, and drying processes that allow combustion products to come into direct contact with food. They can also enter food supply chains through contaminated air and water, and accumulate in various food chains. Regulati ...

PDF 1 MB
Determination of Sulfonamides in Honey

In apiculture, sulfonamides are the most commonly used antibiotics to treat American and European Foulbrood, a type of disease that infects bees. This application note demonstrates how QSight 200 System can provides a very sensitive and robust platform for the analysis of sulfonamides in honey.

PDF 1 MB
PDF 1 MB
Fast and Targeted Analysis of Cell Culture Media Components using QSight LC/MS/MS

Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...

PDF 1 MB
LC/MS/MS: Analysis of Alkylphenol Ethoxylates (APEO) And Alkylphenols (AP) In Textiles

Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...

PDF 2 MB
LC/MS/MS: Improved Throughput and Flexibility for Compliant Drinking Water Analysis with Dual Source Capability

Governing bodies have implemented various directives to monitor acrylamide in drinking water. This also applies in the European Union where the water framework directive and subsequent daughter directives have defined many priority substances, including acrylamide. Compounds chlorate, perchlorate an ...

PDF 1 MB
Measurement of Cortisol & Cortisone in Urine

Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.

PDF 615 KB
Measurement of Homovanillic Acid, Vanillylmandelic Acid & 5-HydroxyIndoleAcetic Acid in Urine

Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.

PDF 678 KB
Pesticide in Grapes by LC-MS/MS

The Grape crop is one of the most important fruit crops consumed in the world. Grapes are consumed both as fresh and as processed products, such as wine, jam, juice, jelly, grape seed extract, raisins, vinegar and grape seed oil. A large variety of pesticides are used in grape production throughout ...

PDF 1 MB
Polymer Applications Compendium

Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category. In this compendium you will find a wide range of applications for po ...

PDF 57 MB
Quantitation of Microcystins and Nodularin in Drinking Water Samples to Meet EPA Method 544 Requirements Using QSight LC/MS/MS

Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...

PDF 901 KB
Quantitation of Pesticide and Mycotoxin Residues in Cannabis as Defined by Seven States Recreational Cannabis Regulations

This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...

PDF 777 KB
Rapid Analysis of Haloacetic Acids in Drinking Water Using UHPLC/MS/MS

Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analytical ...

PDF 1 MB
Simple and Sensitive Method for Determination of Ochratoxin A in Wine by LC/ MS Using QSight Technology

Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...

PDF 924 KB
Simultaneous Determination of Pesticides Residues and Illegal Additives in Wine

Wine can often contain pesticides and fungicides that have been sprayed on the fruits during their growing period. In addition to these contaminants, wine can also contain additives that have been deliberately added during production processes to improve its flavor and color. In this study, a simple ...

PDF 1006 KB
“No Dilute” Just Shoot: Robustness of a QSight LC-ESI-MS/MS for Low Level Pesticide Residue Analysis in Wine

In this study, the QSight LC-MS/MS system was used to evaluate the potential of eliminating sample preparation for trace level pesticide analysis in a complex sample such as wine. We injected undiluted red and white wine samples into the mass spectrometer and studied reproducibility in analysis of t ...

PDF 962 KB

Article

Driving Lab Efficiency and Performance Acceleration with LC/MS/MS

The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...

PDF 438 KB

Brochure

Productivity to the Power of Two - QSight LC/MS/MS System Brochure

When analyzing food and environmental samples, laboratories often need multiple system to get the qualitative and quantitative information on contaminants. But this can result in duplicated sample preparation processes, increased cost of ownership – and suboptimal lab efficiency. Discover the unique ...

PDF 3 MB
QSight Pesticides Analyzer Brochure

Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeonin ...

PDF 9 MB

Ebook

What's in Your Water? PFAS Analysis Explained

Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...

PDF 1 MB

Guide

Tips for Launching a Modern Cannabis Testing Lab

Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...

PDF 285 KB

Poster

Advanced Solutions for Polymers and Plastics

This poster lays out our whole material characterization range for the analysis of polymers and plastics. Find ideal techniques and instruments at each stage in the polymer manufacturing process: Resin Development - Resin Manufacture - Compound Development - Compound Manufacture - Product Forming - ...

PDF 2 MB
Infographic - Solutions for your Toxicology Lab

Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses. FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC ...

PDF 460 KB

Product Note

QSight Simplicity 3Q Software Suite

Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting

PDF 1 MB
QSight Triple Quadrupole LC/MS/MS Preparing Your Lab

Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements

PDF 660 KB

Regulatory Compliance Certification

Webinars